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ea0035p576 | Endocrine tumours and neoplasia | ECE2014

Correlation between atypical pituitary adenomas and Ki-67 Li: clinical and prognostic aspects

Chiloiro Sabrina , Bianchi Antonio , Giampietro Antonella , Iacovazzo Donato , Trapasso Barbara , Piacentini Serena , Tartaglione Linda , Lugli Francesca , De Marinis Laura

Introduction: In 2004, the WHO defined atypical pituitary adenomas (APAs) those with Ki-67 >3%, excessive p53 expression and increased mitotic activity. The usefulness of this classification is still controversial.Aim: To compare the clinical and prognostic features in a series of typical and atypical pituitary adenomas.Materials and methods: We retrospectively reviewed 343 consecutive PAs. APAs represented 18.7% of the cases. ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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